Vitamin B3 pathway may lead to new obesity drugs

Researchers at Beth Israel Deaconess Medical Center say that a newly discovered vitamin B3 pathway could prove fruitful in pursuing new drugs for obesity, diabetes and other metabolic conditions. "Our laboratory investigates the metabolic effects of nicotinamide adenine dinucleotide [NAD+], a metabolite derived from a form of vitamin B3 called nicotinamide," explained senior author Pavlos Pissios. Like resveratrol, which is found in red wine, NAD+ boosts the effects of the protein sirtuin 1 [Sirt1], which is known to provide many health benefits." Release

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