Pitt team redesigns an epilepsy drug

A Pitt team has redesigned the structural components of an existing epilepsy drug--retigabine--in order to make it a more potent, targeted therapy. The older drug activated all 5 types of potassium transport channels in the KCNQ category, but only two were necessary for stabilizing the membranes of brain cells. And the same approach could also work against tinnitus. Release

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