NIH kicks off $110M Knockout Mouse Project

The NIH is kicking off round two in the Knockout Mouse Project, a $110 million, 5-year effort to scramble the genes of thousands of rodents in order to calculate the traits linked to every protein-coding gene in the mammalian genome. That will give scientists a much better idea of the genetic causes of diseases, which in turn could provide a road map for drug developers. "The generation of detailed phenotypic information for each knockout mouse strain will be a boon to disease researchers who want to determine the function of genes and to improve mouse models of human disease," says NIH director Francis S. Collins. Story

Suggested Articles

Treating mice with niacin increased the number of immune cells in glioblastomas, reducing tumor size and extending survival.

Efforts to pivot existing discoveries into COVID-19 cures may not bear fruit until the pandemic has ended but could help fend off future outbreaks.

GigaGen joined a group of companies making plasma-based, polyclonal antibody treatments for COVID-19.