Enzyme in mice linked to obesity, diabetes

Following the theory that Type 2 diabetes is triggered by inflammation, a group of researchers at the German Cancer Research Center concluded that turning off the enzyme Kit prevented a cascade of metabolically linked pathogenic processes. Targeting Kit in mice prevented them from gaining weight and guarded them against insulin resistance. And they're focused on finding the immune cells that produce Kit. "Now we know the key molecule involved in the development of pathogenesis. But we still have to find out which of the various immune cell types are actually involved," says Professor Hans-Reimer Rodewald. Release