CSHL researchers report promising mouse study for Rett syndrome

Professor Nicholas Tonks and colleagues at Cold Spring Harbor Laboratory say that they've seen a promising response to PTP1B inhibitors in mouse models of Rett syndrome, an X-linked disorder that generally kills boys early in life while severely disrupting the lives of girls. And now they're working to determine what beyond glucose regulation is triggered by the inhibitors that could explain the impact this approach has on disease modification. Story