3-D cancer models provides path to animal-free testing; Pesticide-prostate cancer link;

Special Report: The Top 10 Phase III Failures of 2010. Report 

Special Report: FDA's Top Q4 Blockbuster Drug Decisions. Report 

Cancer Research

> Stanford researchers have transformed normal human tissue into three-dimensional cancers in a tissue culture dish. Seeing how cells behave as they divide and invade surrounding tissue will help physicians better understand how human cancers act in the body. The technique also provides a way to test anti-cancer drugs without requiring laboratory animals. Story

> Mustaches are all the rage for "Movember"--a prostate-cancer-awareness and fund-raising campaign. But, the Globe and Mail asks, "Is the mustache distracting from the cause?" Report

> Researchers observed increased prostate cancer risk with specific pesticide use among those with a family history of prostate cancer. Abstract

Genetics

> DNA research says "beauty marks" are more than skin deep. They may also mean you won't age as quickly. Story

> Purdue University scientists have found the last undiscovered gene responsible for the production of the amino acid phenylalanine, a discovery that could lead to processes to control the amino acid to boost plants' nutritional values and produce better biofuel feedstocks. Purdue release

> Binghamton University researchers kick-start ancient DNA. Report

Stem Cells

> The institute that employs James Sherley, one of two scientists who sued to block federally funded stem cell research, is supporting the other side. The Boston Biomedical Research Institute asked to support the government's appeal of a preliminary injunction that temporarily shut down National Institutes of Health-funded research on human embryonic stem cells. Report

> Stem cells and dentistry: an explainer and video. Item

Suggested Articles

Compass' CD137 agonist cleared large tumors in mice that other I-O agents had failed to treat. It's advancing the drug into phase 1 human trials.

UPMC researchers are planning clinical trials of a COVID-19 vaccine that uses pieces of the virus' spike protein to create immunity.

Treating mice with niacin increased the number of immune cells in glioblastomas, reducing tumor size and extending survival.