Scientists from the University Medical Center Hamburg-Eppendorf and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases at the University of Cologne in Germany think they've found a link between age-related dementia and the declining ability of neurons to dispose of unwanted aggregated proteins. In worm and mouse models, they observed that as protein disposal worsens and becomes less efficient with aging, the buildup of these unwanted proteins eventually leads to the development and progression of dementia. The study appears in the March issue of the journal Genetics. Release | Study Abstract