Stryker adds jobs in Michigan; Hospira rises in Q4;

 @FierceMedDev: Attorneys: JNJ knew of mesh problems before marketing. Article | Follow @FierceMedDev

 @MarkHFierce: Medtronic won FDA approval for its next-gen Advisa MRI-friendly pacemaker. Release | Follow @MarkHFierce

 @DamianFierce: More regulatory struggles for St. Jude as it recalls a component of its Amplatzer heart plug. Story | Follow @DamianFierce

> Stryker ($SYK) is expanding its Michigan operations, spending $5.6 million to add 18 jobs to a Portage plant. Article

> Hospira ($HSP) reversed its fortunes in the fourth quarter, posting a $5.3 million net profit after losing $214 million in the same period in 2011. Story

> The U.S. market for in vitro diagnostics is poised to reach $8.6 billion by 2017, according to Millennium Research Group. More

> Insulet has recruited Freescale Semiconductor ($FSL) to design a fully integrated microcontroller to power the second-generation OmniPod, a wireless insulin pump. Release

> GE Healthcare ($GE) has partnered with Vanderbilt University to use its cancer-mapping technology to better understand how tumor cells grow. News

> Agilent ($A) has teamed up with Sera Prognostics to develop proteomic assays for the early prediction of pregnancy complications. Item

> Paragonix Technologies in Cambridge, MA, gained FDA clearance for a device designed to keep a donor heart alive much longer than current technology allows. Story

Biotech News

 @FierceBiotech: In case you missed it: The 25 most influential people in biopharma today - 2013. Special Report | Follow @FierceBiotech

@JohnCFierce: J&J, Pharmacyclics score 'breakthrough' coup with blockbuster hopeful ibrutinib. Article | Follow @JohnCFierce

@RyanMFierce: J&J's Alzheimer's R&D chief sticks by 'golden age' prediction after bapi bust. But where's the data? More | Follow @RyanMFierce

> Early-stage investor Lux targets biotech with new $245M VC fund. Story

> Ziopharm shares spike as PhIII palifosfamide reckoning looms. Story

Pharma News

@FiercePharma: Sanofi plans to boost Lantus production in Ireland with a $59 million upgrade to Waterford site. More | Follow @FiercePharma

@EricPFierce: 2012 M&A was slow in biopharma as cos. choked down previous mega mergers. Execs may be ready to tango in 2013. Special Report | Follow @EricPFierce

@AlisonBFierce: The WHO granted PharmaJet's Stratis Needle-free Injector performance, quality and safety pre-qualification status. Release | Follow @AlisonBFierce

> U.K. gatekeepers shut out Novartis cancer treatment. News

> Discount program robs pharma to pay hospitals, report claims. Story

Drug Delivery News

> Alnylam joins Spanish team to deliver successful RNAi. Story

> Genelux, Sloan-Kettering test delivery of mesothelioma drug. More

> Germany grants reimbursement for Delcath's chemo delivery tech. Item

> UCLA team snuffs cancer cells with nanoshell delivery. News

> Smiths Medical wins FDA clearance for 'smart' infusion pump. Report