San Diego engineers develop biosensor implant for real-time detection of DNA mutation

Engineers at the University of California at San Diego have developed an electrical graphene chip to detect mutations in DNA. It could be the basis of a biosensor chip that can be implanted in the body to offer detection of specific DNA mutations--that would transmit the data to a mobile device in real-time. But a lot of work has to be done first to understand what minute alterations in DNA actually mean when it comes to pathology. "We are at the forefront of developing a fast and inexpensive digital method to detect gene mutations at high resolution--on the scale of a single nucleotide change in a nucleic acid sequence," said Ratnesh Lal, professor of bioengineering, mechanical engineering and materials science in the Jacobs School of Engineering at UCSD, in a statement. This work could eventually add up to a real-time liquid biopsy implant. More