Rainbow Medical’s GluSense picks up $2M for injectable glucose sensor

The Glyde continuous glucose monitoring system is currently in animal studies. Image: GluSense

GluSense, which is developing a long-term glucose-monitoring implant, has received approximately $1.9 million from the newly launched JDRF T1D Fund, according to a spokesman. The company will use the funds to advance its continuous glucose monitoring toward human trials.

“The GluSense Glyde CGM is a highly innovative and promising technology,” said Jonathan Behr, managing director of the T1D Fund, in a statement. “When paired with future advanced artificial pancreas systems or insulin injections, it will reduce the burden of T1D and help those living with the disease maintain blood glucose levels in a safe range.”

JDRF unveiled the $42 million T1D Fund last month. It intends to raise $80 million over the next two years to bankroll the development of promising early-stage treatments for Type 1 diabetes.


Like this story? Subscribe to FierceBiotech!

Biopharma is a fast-growing world where big ideas come along every day. Our subscribers rely on FierceBiotech as their must-read source for the latest news, analysis and data in the world of biotech and pharma R&D. Sign up today to get biotech news and updates delivered to your inbox and read on the go.

The Glyde CGM comprises a glucose-monitoring implant and an external, wearable device. A physician injects the implant just under the skin of a patient under local anesthesia. It is expected to last in the body for one year, continuously measuring glucose levels and communicating data wirelessly to the wearable device, according to the statement.

The implant contains many biosensor protein molecules, which contain two fluorophore groups and a glucose-binding region, according to the company. The percentage of glucose-binding proteins that are bound to glucose at any given moment reflects the concentration of glucose in the environment surrounding the sensor. When this ratio fluctuates, it changes the fluorescence emitted by the implant, which can be read and translated into glucose values by the wearable.

The device is currently in animal studies, the GluSense spokesman said. The investment will support the development of the system and expand on preclincal studies ahead of a first-in-human study, he said.

Like other glucose sensors, the GluSense implant degrades over time. But the company has developed it to replenish itself. The implant contains living cells that produce the glucose-binding protein, so the implant is left with a “relatively constant level of sensing material,” the spokesman said.

Other glucose sensors must be replaced more frequently. For example, the sensor in Medtronic’s MiniMed 670G hybrid closed loop system must be replaced after seven days.

Suggested Articles

The FDA approved a new, tiny pacemaker from Medtronic that does not require the wiring of separate electrodes between the implant and the heart.

The respiratory care company Vyaire Medical has brought on a new CEO, Gaurav Agarwal, following a year of new product launches.

Precision oncology firm Notable Labs is launching its first self-sponsored clinical trial, designed from the ground up to help validate its platform.