The National Center for Complementary and Integrative Health at the U.S. National Institutes of Health (NIH) has proposed conducting large research studies of nondrug pain management approaches. It did so in a report by a working group of the Center's Advisory Council. The research is intended to be in cooperation with the U.S. Department of Defense and the U.S. Department of Veterans Affairs. The group recommended that the proposed research should assess the impact of pain on patient function and quality of life as primary outcomes, with change in use of opioids and other drugs as a secondary outcome. It should also evaluate integrative approaches, as well as options for patients in the early stages of chronic pain. The report follows a series of 5 investigative meetings by the working group. Release