Mindray shakes up top ranks; Urological devices predicted to boom;

 @FierceMedDev: After another quarterly slide, Wright Medical is planning to reorganize. Report | Follow @FierceMedDev

 @MarkHFierce: FDA warns the maker of a light therapy product designed to treat fungal meningitis that the product is unapproved. More | Follow @MarkHFierce

 @DamianFierce: Myriad Genetics is raising its full-year guidance after a strong quarter. More | Follow @DamianFierce

> China's Mindray Medical ($MR) has shuffled its top ranks as co-CEO Xu Hang has resigned, leaving Li Xiting the sole head of the company. News

> Looking to finance its upcoming mitosis, Abbott Laboratories' ($ABT) AbbVie spinoff raised $14.7 billion in the largest dollar-denominated debt issue ever. After the January split, devices and diagnostics will remain under the Abbott moniker, while drug development will fall to the newfangled AbbVie. Story

> The global market for urology devices is poised to explode, according to analysts, predicted to reach $8.6 billion by 2022. Article

> Becton Dickinson ($BDX) has named William Kozy as its new chief operating officer, a position he will fill in addition to his current job as executive vice president. More

> American Medical Systems is recalling some of its AdVance slings in Europe, warning that the sutures they contain may not last as long as labeled. Item

> Medtronic ($MDT) has donated $250,000 to the Red Cross to support victims of Hurricane Sandy. Release

Biotech News

 @FierceBiotech: From FierceVaccines.com: PsiOxus lands $2.7M for ovarian cancer vaccine trial. Item | Follow @FierceBiotech

 @JohnCFierce: Buyout Buzz: The most frequently cited takeover targets in biotech. Special Report | Follow @JohnCFierce

 @RyanMFierce: Crowdsourcing kick spurs interest in NIH drug recycling. More | Follow @RyanMFierce

> PCSK9 rivals Amgen and Pfizer angle for AHA spotlight with promising data. Story

> Takeda snaps up CNS drug developer Envoy Therapeutics in $140M deal. News

> Ambit Biosciences finds $50M more from VCs as leukemia therapy advances. Article

Pharma News

@FiercePharma: Congressional hearings on the meningitis debacle to begin next week. FDA's Hamburg on the sked: Report | Follow @FiercePharma

> Teva shunts Americas chief aside in management shuffle. Article

> Bristol-Myers to slash 480 sales-related jobs in NJ. Story

Biotech Research News

> Failed AstraZeneca drugs gain second chance with $11M U.K. program. News

> UC Davis team finds new lung cancer Rx target. Article

> 'Abdominal imaging window' lets researchers crack cancer metastasis secrets. Story

> Scientists wield stem cells to undo male infertility inflicted by cancer treatment in monkeys. More

Pharma Manufacturing News

> Sigma-Aldrich gets foothold in S. Korea with API deal. Article

> German Bayer partners with Russian drug manufacturer. News

> India's price-setting agency prepares for plant inspections. Story