J&J launches new knee replacement; Sequenom unveils cystic fibrosis diagnostic;

 @FierceMedDev: More worry for Intuitive as MA questions robotic surgery. Item | Follow @FierceMedDev

 @MarkHFierce: Our latest special report: Med Tech's 2012 R&D big spenders. Who made the list? Feature | Follow @MarkHFierce

 @DamianFierce: A House Dem has taken up the medical device tax repeal cause, introducing a bill to kill the charge. Report | Follow @DamianFierce

> Johnson & Johnson's ($JNJ) DePuy unit is unveiling its Attune knee system, a device the company says represents a step forward in total knee replacement technology. Release

> Sequenom ($SQNM) has launched Heredi-T, a cystic fibrosis molecular diagnostic that can analyze 136 mutations tied to disease development. Item

> The FDA approved Guerbet's Dotarem, a novel MRI imaging agent the agency says can help doctors better visualize diseases of the central nervous system. More

> Humanitarians believe PrePex, a nonsurgical circumcision device, can help slash the rates of HIV infection in Africa. Article

> The FDA is debating how best to regulate diagnostic apps, and MedCity News says the 510(k) clearance process seems to be working just fine. Story

> BiosCompass is paying $2.2 million to license Adcon, a surgical gel, from Germany's aap Implantate AG. News

Biotech News

 @FierceBiotech: From FierceBiotechResearch.com: New database a boon for genomics research. Story | Follow @FierceBiotech

 @JohnCFierce: Moderna will now triple its staff in Cambridge, MA, if you're looking for a job. Article | Follow @JohnCFierce

 @RyanMFierce: Celgene makes big splash in gene therapy with two cancer collaborations. News | Follow @RyanMFierce

> Teva touts fresh PhIII evidence of oral MS drug's potential. News

> Enanta prices IPO shares at low end of range. Item

> GlaxoSmithKline reports another batch of weak results for malaria jab. Story

> Gene therapy combats acute leukemia in small study. More

Pharma News

 @FiercePharma: Novartis CEO Joe Jimenez's latest interview with a big media outlet. How $NVS forges ahead, from CNNReport | Follow @FiercePharma

 @EricPFierce: Canada's Apotex, already in NAFTA fight with US over 2009 FDA import ban, finds itself back in the FDA doghouse. Article | Follow @EricPFierce

> Novartis breast cancer drug Afinitor nixed by U.K. gatekeepers. Story

> Compounding pharmacy yanks sterile drugs after repacked Avastin triggered eye infections. News

> AstraZeneca to shed 2,300 jobs in sales, admin as it targets new growth. Report

Pharma Manufacturing News

> Teva returns to market with propofol. Story

> India has plan to meet Europe's new API regs. Report

> Sanofi again having manufacturing issues involving TB drug. Article

> FDA again on Apotex's case for plant problems. More

Vaccines News

> Flexible flu threatens pandemic preparedness. Report

> Anthrax vax vexes bioethics committee. Story

> U.K. smallpox rethink prompts stockpiling criticisms. Article

> Struggle against HPV vaccine skepticism intensifying. More