Keyword: University of Pennsylvania School of Medicine
A University of Pennsylvania team discovered that a protein called TOX helps determine the fate of exhausted T cells in cancer and other diseases.
Scientists from the Children’s Hospital of Philadelphia and UPenn have used CRISPR gene editing to prevent a lung disease in mice before birth.
A Penn team used gene editing to screen for harmful variants of a gene that causes severe hypertrophic cardiomyopathy.
Recent biotech developments include improved viral delivery vehicles for gene therapy and compounds that cripple resistant bacteria.
PARP inhibitors prevent the misplacement of a specific protein that has been implicated in ALS, new research shows.
Biotech developments over the past week include using circulating RNA to predict preemie births and a new way to free up stiffened heart muscle.
A personalized ovarian cancer vaccine was most effective when given alongside a pair of approved cancer meds.
A new CAR-T approach controlled HIV spread and protected T cells from being attacked by HIV in mouse models.
A synthetic DNA vaccine developed by the Wistar Institute and Penn scientists, with support from Inovio and GeneOne, shows promise in human trials.
The past week brought news of discoveries in neuroblastoma, type 1 diabetes and multiple sclerosis.