Keyword: University of Pennsylvania School of Medicine
A Penn team is adapting CAR-T cell therapy to target cardiac fibrosis, and they have promising early results in rodents.
Blocking a protein called ATF4 in tumors driven by the gene MYC causes so much stress to cancer cells that they die, Penn researchers found.
A University of Pennsylvania team discovered that a protein called TOX helps determine the fate of exhausted T cells in cancer and other diseases.
Scientists from the Children’s Hospital of Philadelphia and UPenn have used CRISPR gene editing to prevent a lung disease in mice before birth.
A Penn team used gene editing to screen for harmful variants of a gene that causes severe hypertrophic cardiomyopathy.
Recent biotech developments include improved viral delivery vehicles for gene therapy and compounds that cripple resistant bacteria.
PARP inhibitors prevent the misplacement of a specific protein that has been implicated in ALS, new research shows.
Biotech developments over the past week include using circulating RNA to predict preemie births and a new way to free up stiffened heart muscle.
A personalized ovarian cancer vaccine was most effective when given alongside a pair of approved cancer meds.
A new CAR-T approach controlled HIV spread and protected T cells from being attacked by HIV in mouse models.