Keyword: University of Pennsylvania
Scientists running the first trial of CRISPR-edited cells to fight cancer are reporting that the therapy has been well tolerated by three patients.
Tmunity is coming back to the well for a $75 million series B that will take it into phase 2 studies in 2021.
University of Pennsylvania scientists designed CAAR-T cells to only target the cells that express autoantibodies in autoimmune diseases.
A Penn team is adapting CAR-T cell therapy to target cardiac fibrosis, and they have promising early results in rodents.
The James Wilson-founded gene therapy startup has reeled in another $110 million to take several assets into the clinic.
Blocking the enzyme CDK7 could be a new way to overcome resistant prostate cancer, and one drug is already in trials.
UT Southwestern researchers uncovered a mechanism by which PARP inhibitors attack cancer, suggesting they could be used in more patients.
Blocking a protein called ATF4 in tumors driven by the gene MYC causes so much stress to cancer cells that they die, Penn researchers found.
A University of Pennsylvania team discovered that a protein called TOX helps determine the fate of exhausted T cells in cancer and other diseases.
Amicus plans to build an R&D center in the heart of Philadelphia’s University City, not long after inking a $100 million deal for 10 gene therapies.