Keyword: University of Maryland
Understanding how some helper T cells become killer T cells could lead to better vaccine design for HIV and hep C.
The past week ushered in new discoveries of key cancer gene mutations and the T cells behind autoimmune diseases.
Scientists at the University of Maryland have identified thousands of cancer-causing genetic mutations using a method that may lead to new targeted treatments.
Poly(ADP-ribose) polymerase inhibitors (PARPis) are an exciting class of cancer drugs currently used in the clinic. To date, however, patients with acute myeloid leukemia--a cancer with a notoriously poor outcome after diagnosis--have failed to respond to them. Scientists have recently shown that combining PARPis with an epigenetic modifier significantly reduces cancer growth and survival of leukemia cells.
University of Maryland researchers have manipulated lymph nodes to “switch off” autoimmune attacks in diseases like multiple sclerosis while preserving healthy immune function.
Scientists from the University of Leicester and the University of Maryland have reversed Alzheimer’s and Parkinson’s symptoms by inhibiting an enzyme in fruit fly models, highlighting a new avenue to treat neurodegenerative diseases.