Keyword: UC San Diego School of Medicine

Mature neuron

New Huntington’s disease model hints at novel therapeutic target

Neurodegenerative diseases like Huntington’s (HD) have lacked effective therapy, in part due to the difficulty in recapitulating the disease in a laboratory setting. Now a team of scientists has created a new model of HD and in doing so, discovered a protein subunit that may reverse the disease model.
An outline of a mouse heart

Computing powerhouses find new receptor binding sites in heart failure

Current heart failure therapy is limited by serious side effects. Researchers have now designed a computational approach to characterize protein structures that are targets for heart failure drugs. The results may lead to better drug development: compounds that can subtly fine-tune the heart, without the side effects.