Massive NCI database links cancer genes with drugs

The National Cancer Institute (NCI) has taken steps to tie together drug effects and genetic variants in cancers in an enormous database, as research of targeted attacks on tumors have yielded a dizzying amount of info on the vast genetic diversity within malignancies and the compounds that block drivers of disease. A study involving the database was published in the journal Cancer Research. "To date, this is the largest database worldwide, containing 6 billion data points that connect drugs with genomic variants for the whole human genome across cell lines from nine tissues of origin, including breast, ovary, prostate, colon, lung, kidney, brain, blood and skin," said Dr. Yves Pommier, chief of the NCI's Laboratory of Molecular Pharmacology, as quoted in a press release. "We are making this data set public for the greater community to use and analyze." Release | Here's the story from FierceBiotechResearch

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