Synergy reports PhIIb/III success for constipation drug; Warburg Pincus pays $195M for JHP;

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> Shares of Synergy Pharmaceuticals ($SGYP) got a big boost today after the biotech announced that its Phase IIb/III study of an experimental therapy for chronic idiopathic constipation (CIC) hit its primary and key secondary endpoints. The developer held back the data for an upcoming scientific meeting but maintained that lead drug plecanatide significantly increased "the number of complete spontaneous bowel movements" along with impacting stool consistency, straining and time to first bowel movement in patients with CIC. The drug is being billed as a potential competitor to Ironwood's Linzess (linaclotide). Shares were up 13% today in midmorning trading. Release

> Private equity player Warburg Pincus has stepped in to buy contract manufacturing company JHP Pharmaceuticals for $195 million. JHP manufactures injectable products for clinical trials as well as for commercial distribution. Release

> Vernalis says that it has achieved a third milestone in its drug discovery collaboration with H. Lundbeck, triggering payment of £0.75M. Release

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