Regeneron files an RA antibody for FDA approval; Dimension leases a new R&D hub;

@FierceBiotech: Biogen spells out its moonshot R&D strategy amid deep cost cuts. More | Follow @FierceBiotech

@JohnCFierce: Oxford team spotlights promise of AstraZeneca drug in targeting cancers. FierceBiotechResearch article | Follow @JohnCFierce

> Regeneron Pharmaceuticals ($REGN) has filed sarilumab, an antibody for rheumatoid arthritis, for FDA approval. More

> Allergan ($ACT) paid an undisclosed sum for Northwood Medical Innovation to get its hands on a CE-marked aesthetic device to correct prominent ears. News

> Dimension Therapeutics ($DMTX) has leased a 17,475-square-foot R&D outpost in Woburn, MA. Item

Medical Device News

@FierceMedDev: Roche launches rapid HIV, hep C tests in Europe. Article | Follow @FierceMedDev

@VarunSaxena2: Medtronic releases health economics study of its drug-coated balloon at Las Vegas conference. Story | Follow @VarunSaxena2

@EmilyWFierce: Does AstraZeneca own the color purple? On a pill, yes, the company contends. FiercePharmaMarketing story | Follow @EmilyWFierce

> Theranos CEO heeds call for transparency for proprietary technology. Article

> Medtronic axes 150 jobs in new Irish tax domicile. News

Pharma News

@FiercePharma: GSK's vaccine unit sees revenue, profit jump in Q3. More from FierceVaccines | Follow @FiercePharma

@CarlyHFierce: Good thing Bayer's in Germany, CEO says. U.S. business culture is too impatient. Story | Follow @CarlyHFierce

> McCaskill turns up heat on Valeant with Senate pricing probe. Story

> Novo adding 450 more Denmark jobs as its bets on growth in insulin demand. Article

Pharma Marketing News

> GlaxoSmithKline's HIV bright spot could get brighter with new Tivicay combo meds. Item

> Viewers skeptical of DTC ads, but they drive people to docs anyway. More

> Bristol-Myers Q3 ad spending pushes up to $193M on renewed promotions push. Story

> Pfizer launches first Prevnar TV spot to bring in the 50-plus crowd. Report

> Does AstraZeneca own the color purple? On a pill, yes, the company contends. Article

Biotech Research News

> Neat 'trick' guards peptides against early degradation. Story

> JAK inhibitors target senescent cells in aging study. Item

> Small molecule used to blunt glioblastoma growth in mice--UCSD. More

> Researchers devise heat-triggered liposome 'grenades' to destroy cancer cells. Story

> UPenn researchers show importance of calcium signaling for Ebola virus. Article

Vaccines News

> Takeda, Hilleman eye low-cost vaccine space. News

> Sanofi expects first dengue vaccine license in Q4. Item

> Pfizer teams up with the Biovac Institute to produce Prevenar 13 in South Africa. Report

> GSK's vaccine unit sees revenue, profit jump in Q3. Story

> European Commission launches €23M HIV vaccine research initiative. Article