Provectus Pharmaceuticals' Patent Application Published for Combining Local and Systemic Therapies for Enhanced Treatment of Cancer

Provectus Pharmaceuticals' Patent Application Published for Combining Local and Systemic Therapies for Enhanced Treatment of Cancer

Provectus Pharmaceuticals, Inc.Peter R. Culpepper, CFO, COOPhone: 866-594-5999 #30orPorter, LeVay & Rose, Inc.Marlon Nurse, DM, SVP – Investor RelationsBill Gordon, SVP – Media RelationsPhone: 212-564-4700

Provectus Pharmaceuticals, Inc. (OTC BB: , ), a development-stage oncology and dermatology biopharmaceutical company, announced that a patent application has been published for U.S. and international patents covering the combination of local and systemic immunomodulative therapies for cancer treatment.

The patent, entitled "r," covers a method of treatment of cancer that comprises administering a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition in combination with a therapeutically effective amount of a systemic immunomodulatory anticancer agent. The systemic immunomodulatory anticancer agent comprises anti-CTLA-4 antibodies including ipilimumab and tremelimumab.

Dr. Craig Dees, PhD, CEO of Provectus said, “We are pleased that this joint patent application has been published as we continue to develop our intellectual property claims. We are excited about the potential of combining PV-10, our intralesional chemoablative therapy, with other anticancer agents as appropriate, and expanding its use in broader applications."

This patent can be accessed at the following link:

Provectus Pharmaceuticals specializes in developing oncology and dermatology therapies. Its novel oncology drug PV-10 is designed to selectively target and destroy cancer cells without harming surrounding healthy tissue, significantly reducing potential for systemic side effects. Its oncology focus is on melanoma, breast cancer and cancers of the liver. The Company has received orphan drug designations from the FDA for its melanoma and hepatocellular carcinoma indications. Its dermatological drug PH-10 also targets abnormal or diseased cells, with the current focus on psoriasis and atopic dermatitis. Provectus has recently completed Phase 2 trials of PV-10 as a therapy for metastatic melanoma, and of PH-10 as a topical treatment for atopic dermatitis and psoriasis. Information about these and the Company's other clinical trials can be found at the NIH registry, . For additional information about Provectus please visit the Company's website at or contact Porter, LeVay & Rose, Inc.

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