Pfizer looked into a GSK buyout, FT says; Regulus plots hep C combo study;

@FierceBiotech: ICYMI yesterday: Merck KGaA inks cancer metabolism drug discovery alliance with Selvita. Article | Follow @FierceBiotech

@JohnCFierce: Gates, Hopp back $110M megaround for CureVac's mRNA work. News | Follow @JohnCFierce

@DamianFierce: Wait can we reconvene Grantland just to deal with this image? More | Follow @DamianFierce

> Before taking up buyout talks with Allergan ($AGN), Pfizer ($PFE) made an overture at GlaxoSmithKline ($GSK), according to the Financial Times. Story

> Regulus Therapeutics ($RGLS) and partner GlaxoSmithKline are planning a Phase II study combining their respective hepatitis C therapies RG-101 and GSK2878175. News

> Viking Therapeutics ($VKTX) launched a Phase II study of the bone-boosting VK5211 in patients who recently suffered hip fractures. More

Medical Device News

@FierceMedDev: ICYMI: Drug-device combo from Wyss takes a new approach on treating stroke. FierceBiotechResearch story | Follow @FierceMedDev

@EmilyWFierce: Flowonix teams with Connecticut provider for implant of drug delivery infusion pump. Article | Follow @EmilyWFierce

> Neuromodulator and artificial kidney to be reviewed under FDA's Expedited Access Pathway. More

> Fractyl gains traction with balloon ablation device for Type 2 diabetes. Article

Pharma News

@FiercePharma: ICYMI yesterday: FDA cites Pfizer for shortfalls at Chinese manufacturing plant. Article | Follow @FiercePharma

@CarlyHFierce: ICYMI yesterday: Express Scripts looks into pharmacies at AbbVie, Teva in wake of Valeant's Philidor saga. Article | Follow @CarlyHFierce

> In snit over supply, not prices, MSF urges South Africa to override AbbVie drug patent. Article

> Pfizer flirted with a GSK megabid, but got rejected: FT. Story

Drug Delivery News

> Amgen's Imlygic becomes first re-engineered virus to earn FDA approval as a cancer fighter. Item

> Pfizer's sickle cell anemia candidate enters trials, to the delight of delivery partner Halozyme. Story

> Imaging nanoparticle puts the heat to ovarian cancer cells. Article

> Investigational drug enables faster absorption of bioresorbable drug-eluting stents. Report

> Novartis' inhaler for COPD gets FDA approval. More

Pharma Manufacturing News

> Bain-backed compounding upstart adds second Texas manufacturing facility. Item

> Struggling Daiichi again stumbles with vaccine production. More

> First prefab biologics plant goes up in China, in 11 days. Report

> Roche completes Shanghai plant expansion, starts on new project. Story

> FDA uncovers issues at Pfizer China plant after banning products from its JV partner. Article

Pharma Asia News

> China State Council briefing outlines multilevel system for medical treatment. More

> MabSpace gets $15M as Lilly Asian Ventures bets on immune approach. Story

> China's WuXi PharmaTech, Gilead focus on analytical testing in wider partnership. Article

> HK-based Chi-Med wraps up PhI healthy volunteer trial of HMPL 523. More

> China's Biomab Holding, India's Cipla go separate ways on biosimilars. Report