News of Note—Aeterna review, Allegro eye test and Ocugen orphan tag

> Troubled Aeterna Zentaris, in the midst of a legal battle with its former CEO and major problems with its leading candidate, has announced a strategic review to “consider and evaluate various strategic and financing,” as well as “considering and recommending changes to the company’s management and governance.” Release

> Allegro Ophthalmics says the second stage of the phase 2b test of its leading eye drug Luminate hit its primary endpoint when used as a sequential therapy in patients with diabetic macular edema. Statement

> Ocugen says the FDA has been handed an orphan drug designation for its med OCU300 (brimonidine tartrate) in patients with ocular graft versus host disease. It works as a repurposed drug, which the biotech says can help up to 90% of patients “without significant side effects.” Release