Merck Provides Update on the IMPROVE-IT Vytorin Trial

Merck Provides Update on the IMPROVE-IT Trial
WHITEHOUSE STATION, N.J., March 11, 2010 -- Merck & Co., Inc. today said that the Data Safety Monitoring Board (DSMB) of the IMPROVE-IT study has performed a pre-specified interim analysis of efficacy data and also reviewed safety data from the IMPROVE-IT trial and has approved continuing the study. The interim efficacy analysis was conducted by the DSMB after the trial had reached approximately fifty percent of the 5,250 pre-specified clinical endpoints called for in the study design. Merck remains blinded to the actual results of the interim analysis and other IMPROVE-IT data.

In addition, Merck also said that nearly 17,000 patients worldwide have been successfully enrolled in the ongoing IMPROVE-IT clinical trial.

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