Investigators report success for Seaside's fragile X drug; Leukemia Society backs Constellation work on BET inhibitor;

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> Seaside Therapeutics, one of this year's Fierce 15 companies, has snagged important animal and human data that underscores the potential of its experimental therapy for fragile X syndrome, which can cause a form of autism. Scientists say that STX209 corrected genetic abnormalities engineered in mouse models of the disease. And among a small group, patients taking the drug registered a significant improvement on a key "social avoidance" measure. "We think this is a great drug," says co-author Dr. Randi Hagerman. Story

> Constellation Pharmaceuticals is getting $7.5 million from The Leukemia & Lymphoma Society to fuel work on a BET inhibitor for the treatment of hematologic malignancies. Release

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And Finally… The Archives of Disease in Childhood reports that new research shows that obese kids "have less sensitive taste-buds than kids of normal weight." Release