ICON Appoints Dr. Dariush Elahi As Head Of Metabolic Research, Early Phase

Dublin, Ireland, 20 January, 2014 – ICON plc, (NASDAQ: ICLR) a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries, today announced the appointment of Dr. Dariush Elahi as Director of Metabolic Research. Based in ICON's Clinical Pharmacology Unit in San Antonio, US, Dr. Elahi will lead ICON's early phase glucose clamping programs globally, providing expert, scientific consultation to sponsors who are developing therapeutic agents to treat endocrine/metabolic disease.

Dr. Elahi is a clinical physiologist with over 30 years of research experience, predominantly focused on translational investigations of the regulation of glucose homeostasis in states of glucose tolerance and intolerance. His research has included the study of volunteers with "normal "glucose tolerance, obesity, type II diabetes mellitus, and aged volunteers with varying degrees of insulin resistance and beta cell dysfunction. Dr. Elahi is an expert with respect to the methodologies used to conduct these types of investigations, including various clamp techniques (Hyperinsulinemic / Euglycemic, Time-Action Profile, Hyperglycemic, Hypoglycemic, Pancreatic), the MinMod technique, as well as measurements of relevant hormones byRIA and ELISA. His expertise includes kinetics analyses of fuel substrates using both stable and radioactive tracers and the employment of these techniques during clamp studies.

Dr. Elahi has authored 147 scientific publications and is nationally and internationally recognised for his work on the role of insulin. He has received academic appointments as a professor at several prestigious institutions, including The Johns Hopkins University School of Medicine, Harvard Medical School, and the University of Pennsylvania's Perelman School of Medicine. He has also served as Research Physiologist and Senior Staff Fellow at the National Institutes of Health (NIH) and National Institutes on Aging.

Dr. Elahi earned a Master of Science in Biology at American University in Washington, D.C. After earning a Doctorate in Physiology at Dalhousie University in Nova Scotia, he completed a Post-doctoral Fellowship in Physiology at Louisiana State University Medical Center and at the National Institute on Aging.

About ICON plc

ICON plc is a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries. The company specialises in the strategic development, management and analysis of programs that support clinical development - from compound selection to Phase I-IV clinical studies. ICON currently has approximately 10,300 employees, operating from 77 locations in 38 countries.

Further information is available at www.iconplc.com

ICON Media Contact
Genevieve Tuck
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