Helsinn U.S. names new CEO, sales chief

William Mann, Ph.D., has been appointed as the new CEO of Helsinn Therapeutics, U.S. Mann was already chief operating officer of the recently acquired Helsinn Therapeutics. Helsinn also hired William Brown as vice president of commercial operations USA, to build a Helsinn Therapeutics direct sales structure in the United States. Helsinn release

In a big management shuffle, Roche announced that Ian Clark would jump from his post as head of global product strategy for pharmaceuticals to CEO of Genentech. He replaces Pascal Soriot, who has managed the integration of Genentech into Roche. Soriot was named COO of Roche pharma. Story

Timothy Mayleben has been named CEO of Ann Arbor-based Aastrom Biosciences. He replaces George Dunbar, who has been appointed chairman of the board. Report

Constellation Pharmaceuticals has appointed Edward E. Harlow, Jr., Ph.D. as the company's chief scientific officer. Constellation release

KV Pharmaceutical has named Thomas McHugh, the company's vice president of finance and corporate controller, as its interim chief financial officer. KV Pharma release

Vivalis named Philippe Rousseau as its new chief financial officer. Vivalis release

Enzo Biochem has named Mohan Chellani, Ph.D., formerly a senior manager with Quest Diagnostics, as vice president of scientific affairs at its Enzo Clinical Labs subsidiary. Enzo release

Shenzhen Beike Biotechnology announced the appointment of two senior stem cell scientists to key positions in the company. Li Tao, Ph.D., joins as lab director of the iPS (induced Pluripotent Stem Cell) Laboratory, and Susan Jiang, M.D., Ph.D., has been named chief science officer. Release

Thomas R. Kassberg has joined Rib-X Pharmaceuticals as chief business officer. Rib-X release

Celldex Therapeutics, a biopharmaceutical company, has appointed Larry Ellberger as its new board chairman. Charles Schaller will remain on the board as a director for the remainder of his term. Story

GENova Biotherapeutics, a biotechnology company, has appointed John Savin as its new vice president. GENova release

MDRNA named June Ameen as vice president corporate development. MDRNA release

Bengt Winblad, M.D., Ph.D. has joined United BioSource's European Scientific Advisory Board for CNS Clinical Trials. Release