Flush with cash, Sanofi may look for a deal; Puma eyes $120M in offering;

@FierceBiotech: Another 5 biotechs are queuing up for $278M in IPOs. Is this a bubble after all? More | Follow @FierceBiotech

@JohnCFierce: I'm happy to see the IPO boom, the rise in valuations and all that. But with booms, the bigger they are, the harder they fall. Don't forget. | Follow @JohnCFierce

@DamianFierce: The FDA is giving Sprout's female libido drug another shot in what is becoming a pretty interesting case study. Coverage | Follow @DamianFierce

@EmilyMFierce: The top 10 biomedical research organizations, ranked by NIH funding. Special report | Follow @EmilyMFierce

> Now that it's unlikely Sanofi ($SNY) will stage a huge buyback of shares held by L'Oreal, analysts wonder what the French drugmaker will do with a boatload of cash, figuring the company might make an M&A splash. News

> California's Puma Biotechnology ($PBYI) is looking to raise about $120 million through a public offering. More

> Perhaps unsurprisingly, Ariad Pharmaceuticals' ($ARIA) up-and-down fortunes with Iclusig landed it on top of a list of the most volatile stocks. Article

> Recro Pharma has filed for a $28 million IPO, looking to bankroll its pipeline of pain drugs. Story

Medical Device News

@FierceMedDev: St. Jude Medical's stock spiked again after an analyst upgrade. Story | Follow @FierceMedDev

@MarkHFierce: FierceBiotechResearch's latest--a look at the top 10 U.S. biomedical research institutions. Report | Follow @MarkHFierce

@MichaelGFierce: Sonrgy grabs rights to UCSD-created ultrasound-nanocarrier tech. Item from FierceDrugDelivery | Follow @MichaelGFierce

@EmilyWFierce: ConvaTec is closing its New Jersey facility and cutting jobs. Story | Follow @EmilyWFierce

> Two major Dx players in Brazil are on the cusp of major changes. Item

> Surgeons have implanted a 3-D-printed pelvis into a U.K. cancer patient. More

> Smiths Medical adds tracheostomy tubes designed for kids to standard product line. News

Pharma News

@FiercePharma: Perrigo sees growth, but its sales are trimmed by a hit to contract manufacturing. Story | Follow @FiercePharma

@TracyStaton: Double dose of Merck is too much for German version's CEO. Article | Follow @TracyStaton

@EricPFierce: The best biomedical research facilities in the US may not surprise you. Then again maybe it will. Report | Follow @EricPFierce

@GalenMoore: Particularly for drugmakers strong in diabetes, the Gulf region is a hotbed of activity. Story | Follow @GalenMoore

> Mallinckrodt expands pain portfolio with Cadence acquisition. Piece

> Double dose of Merck is too much for German version's CEO. Story

> What's Big Pharma's latest hot spot? The Middle East. Article

> Pharma-funded group hired by U.K. health service to advise on strategy. News

Biotech Research News

> The top 10 biomedical research institutions. Special Report

> CalTech drug delivery method halts HIV infection in mice. Article

> Nasal vaccine protects mice from West Nile virus. Story

> U.K. pledges to reduce use of animals for biomedical research. News

> Gates Foundation delivers an $11.8M grant to fuel tuberculosis R&D. Story

> New therapeutic target for multiple sclerosis could help repair damaged brain cells. Article

Pharma Manufacturing News

> FDA says products recalled by compounder are contaminated. News

> Teva, which has been tightening its supply chain, turns in a surprising financial report. Story

> Jazz is investing up to $68M to build its first manufacturing facility. Article

> Wockhardt's earnings crash under the weight of FDA bans. News

> The FDA reports far fewer new drug shortages, but the problem continues to grow. Article

> Novartis is expanding a plant in Singapore. Item


Suggested Articles

In this week's EuroBiotech Report, AstraZeneca plans 2020 lupus filing, Roche's SMA trial hits endpoint and Kiadis cuts staff in R&D pivot.

In our EuroBiotech roundup this week, NEC and Vaximm ink cancer vaccine pact, Compugen posts cancer data and Lunac raises cash.

Biotech venture fund ATAI Life Sciences has partnered with artificial intelligence drug discovery specialist Cyclica to form a new JV.