FDA puts Bayer's riociguat app on fast track; Resverlogix spins off epigenetics drug platform;

@FierceBiotech: Pharmacyclics bounces higher as J&J wins third 'breakthrough' cancer drug coup. More | Follow @FierceBiotech

@JohnCFierce: Roche rolls out $392M Isis pact in two-prong attack on Huntington's. Story | Follow @JohnCFierce.

@RyanMFierce: Uh oh. biotech outfit Unigene is slashing ~40% of workers to extend cash runway. Release | Follow @RyanMFierce

> The FDA has granted a priority review for Bayer's riociguat, a new drug for pulmonary hypertension. Story

> Canada's Resverlogix (TSX:RVX) is spinning off a subsidiary and splitting its lead program for RVX-208 and its epigenetics platform. RVX Therapeutics will get the platform with a game plan targeting new programs for autoimmune diseases and cancer. Release

> The number of clinical trials being mounted in Australia dipped again last year, raising worries about the health of the country's biotech industry. Story

> Anthera Pharmaceuticals ($ANTH) has secured a $20 million debt financing facility through a syndicate led by MidCap Financial SBIC. Release

Pharma News

@FiercePharma: Merck's new Fosamax trial starts today. Was woman's atypical femur fracture caused by drug, or disease? More | Follow @FiercePharma

@EricPFierce: India delays to 2014 its deadline for drugmakers to put bar codes on primary packaging to fight fakes. More | Follow @EricPFierce

> Merz drops out of Obagi bidding, handing $417M deal to Valeant. News

> U.S. drugmakers Pfizer, J&J top reputation ranks in Germany, Italy. Story

> Orphan drugs join the price-squeeze club in Europe. Report

Medical Device News

 @FierceMedDev: 'Awake Imaging' boosts Dx prospects for fidgety patients. Article | Follow @FierceMedDev

 @MarkHFierce: BSD will use Japan's Terumo to reach global markets with its cancer ablation device. More | Follow @MarkHFierce

 @DamianFierce: Quintiles' founder and early investors will make off with $25M once the CRO goes public. Story | Follow @DamianFierce

> FDA: Woman with HeartWare HVAD dies after device loses power. Article

> Penn Medicine rolls out personalized diagnostics. Item

> 'Awake Imaging' boosts Dx prospects for fidgety patients. More

> Cancer Genetics bags $6.9M in over-allotted IPO. Story

CRO News

> InVentiv sells sample management biz to Knipper. More

> Indian trial reform on the way, but does it make sense? Article

> EU CRO TranScrip launches U.S. operation. Item

> AmerisourceBergen sells contract packaging biz for $308M. More

> Bristol-Myers picks LabCorp for CRO work. Story

Biotech IT News

> Survey: Cloud computing tops pharma's IT plans. More

> Life Tech genome software aids cancer-drug hunters in pharma. Report

> New trial search engine steps into congested market. Story

> Big Data hits Eastern Europe as IBM fires up supercomputer. Item

> Computational scientists clear path to potential Parkinson's drugs. Article

And Finally… Hong Kong officials are on high alert as new cases of H7N9 bird flu spread among humans. Seven have died from the new bird flu strain, which is raising alarm throughout China. Story