EuroBiotech: More Articles of Note


> Nanobiotix created a subsidiary, Curadigm, to step up the use of nanoparticles to improve drug safety and bioavailability. Statement 

> Freeline posted preclinical data on its Fabry disease gene therapy. A single dose of the therapy sent GLA levels up to 1,061-fold higher than those of wild-type mice. Release 

> Transgene completed enrollment in a phase 2 trial that is testing TG4010 in combination with Opdivo. The milestone sets Transgene up to report primary endpoint data later this year. Statement  


De-risking the Development of Biotherapeutics Using Early Stage In Vitro Expression and Genetic Characterisation Tools

There is a high attrition rate during the development of biotherapeutics impacting the high cost of development. Early identification of the preferred expression host for manufacturing, along with lead candidate screening and material supply can help to reduce both attrition rates and cost.

> Mereo BioPharma posted six-month data from the open-label arm of a phase 2b trial in brittle bone disease. The data suggest setrusumab may improve bone density when Mereo reports data from the full study later this year. Statement 

> Orchard Therapeutics secured the worldwide license to an autologous hematopoietic stem cell gene therapy program for the treatment of Mucopolysaccharidosis Type I. Release  

> F-star completed the dose escalation phase of its FS118 study without seeing dose-limiting toxicities. Release 

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