@FierceBiotech: Top 10 mega-rounds fuel record VC pace, with a distinctly ex-U.S. biotech accent. Report | Follow @FierceBiotech
@JohnCFierce: And in case you missed it: Eleven Bio faces cash crunch as lead drug flunks another PhIII. Article | Follow @JohnCFierce
@DamianFierce: Index Ventures' official Dick Costolo announcement is a link to his tweets of screenshots from his notes app. More | Follow @DamianFierce
> Canada's iCo Therapeutics is cutting its entire staff in an effort to conserve cash, demoting its executives to consultants after failing to secure a buyout. More
> Denali Therapeutics, working off of a $217 million funding round, has leased the entire first floor of a new life sciences hub in the Bay Area. Story
> U.K. startup Centauri Therapeutics is getting off the ground with plans to develop new therapies for infectious diseases, securing £3 million ($4.3 million) in investor commitments to move forward. News
Medical Device News
@FierceMedDev: Second activist investor buys 5% stake in HeartWare, putting Valtech deal in doubt. Article | Follow @FierceMedDev
@VarunSaxena2: Interesting article in @TheEconomist. Which lifesci hub do you think is no. 1? More (reg. req.) | Follow @VarunSaxena2
@EmilyWFierce: Shkreli, Valeant CEO set for a grilling at Congressional price-hike hearing. FiercePharma story | Follow @EmilyWFierce
> Startup raises $19M to market suture-replacing, Zip skin closure products. Report
> J&J axes 3,000 jobs in bid to save $1B and revive lagging medical devices business. Article
Pharma News
@FiercePharma: New strain of avian flu confirmed in Indiana poultry flocks. FierceAnimalHealth item | Follow @FiercePharma
@EricPFierce: FDA says this Hong Kong plant pretty much had not quality control in place. FiercePharmaManfacturing story | Follow @EricPFierce
@CarlyHFierce: ICYMI: PTO shuts down Amgen's Humira IP challenge. Article | Follow @CarlyHFierce
> Shkreli, Valeant CEO set for a grilling at Congressional price-hike hearing. Report
> Supreme Court rebuffs another J&J appeal, leaving $140M failure-to-warn judgment intact. Article
Animal Health News
> New strain of avian flu confirmed in Indiana poultry flocks. Story
> Affymetrix teams with Bio-Genesys to offer genetic testing for livestock. More
> Animal drugs, diagnostics and distribution on display at J.P. Morgan confab. Item
> EMA launches review of 'last-resort' antibiotic after scientists ID resistance gene. Report
> Dechra's growth spurt continues with $6M acquisition of Mexican manufacturer. Article
Biotech IT News
> BioMed X emerges from Merck KGaA alliance armed with bioinformatics tools. News
> NIH kicks off $313M genome sequencing drive. Report
> Illumina moves into semiconductor-based sequencing with Project Firefly. More
> Biden puts data sharing at center of drive to cure cancer. Article
> Astellas hooks up with NuMedii to continue drug repurposing deal drive. Story
Drug Delivery News
> Dental anesthesia delivered via electric current could offer needle-free alternative. Item
> Will FDA panel's second recommendation of approval for implant to treat opioid addiction be enough? More
> Takeda teams up with enGene for gastrointestinal gene delivery R&D. Report
> Catalent to earn up to $618M under antibody-drug conjugate research alliance with Roche. Story
> Pfizer invests in 4D Molecular Therapeutics, a maker of gene delivery vectors. Article
Pharma Manufacturing News
> Mylan halts production at Poland plant after inspectors uncover problems. News
> Plant-based biologics production to be offered by new CMO. Item
> FDA slams another Chinese drugmaker with a warning letter. Story
> Emcure, which has issues with FDA, buys Canadian firms. Report
> Wockhardt's new sterile injectable plant issued a Form 483 by the FDA. Article
Pharma Asia News
> Unit of Singapore's Biosensors refuses U.S. FDA inspection. Item
> Redesigned scope by Japan's Olympus cleared by FDA. More
> Japanese drugmakers shift focus as government pushes for more generics. Report
> Sanofi may get waiver from large-scale dengue vaccine trials in India. Story
> Healthcare reform in China raises tensions between hospitals, pharma companies. Article