What did you miss during the Christmas break? The short answer: Not much. The last week of the year is usually highlighted by a few last-minute deals that need to be reported ahead of New Year's day. But evidently any big deals in the offing have been reserved for the lead-up to JP Morgan. The news in biotech centered around a few key setbacks and a cleanup on aisle Shkreli. We reported that Chimerix's ($CMRX) lead therapy failed a key Phase III study, which sent its shares into meltdown mode. KaloBios is back on the brink after Martin Shkreli's disastrous rescue attempt, filing for bankruptcy protection. And the small Alzheimer's player Anavex revealed that the SEC is investigating the company, apparently focusing on suspicious trading activity involving their shares.