@FierceBiotech: GlaxoSmithKline loses its first big PhIII bet on heart drug darapladib. News | Follow @FierceBiotech
@JohnCFierce: Sarepta down 58%--about $700M in market cap vanished. | Follow @JohnCFierce
@DamianFierce: Dendreon slashing about 200 more jobs as Provenge sales slide and buyer interest comes up short. More | Follow @DamianFierce
@EmilyMFierce: New drug target identified for glioblastoma. More | Follow @EmilyMFierce
> A Galapagos subsidiary, BioFocus, has forged a three-year agreement with Biogen Idec ($BIIB) to explore new therapies for the autoimmune disease scleroderma. The deal is worth up to $31 million. Release
> Alnylam ($ALNY) won fast-track status for patisiran, an experimental therapy for a rare heart and kidney disease. Report
Medical Device News
@FierceMedDev: Solta's aesthetic device sales sag, prompting company to explore selling itself. More | Follow @FierceMedDev
@MarkHFierce: ICYMI: Don't over-promise on what your medical device can deliver. Via BBJ. Story | Follow @MarkHFierce
@MichaelGFierce: ICYMI: Chinese investors pursue groundbreaking med tech from Canada's MDI. Article | Follow @MichaelGFierce
> Report: Boston Scientific leads $20M round for Israeli devicemaker. More
> Rise in reported surgical robot problems could spur training surge. Item
> Hologic tanks as $1.1B charge wipes profits. News
Pharma News
@FiercePharma: Breakthrough hep C meds aren't yet for sale, but critics already taking aim at prices. Article | Follow @FiercePharma
@EricPFierce: AstraZeneca thinks there is no place like home for new Zoladex plant. Story | Follow @EricPFierce
@CarlyHFierce: Rare-disease co. ViroPharma finally snatched up after lots of speculation--Shire gets it for $4.2B. Release | Follow @CarlyHFierce
> For-sale Dendreon slashes 150 jobs, cuts more costs in hunker-down move. More
> Embattled Teva settles one thorny problem with $718M Israeli tax deal. News
Pharma Manufacturing News
> AstraZeneca stays in England with $190 million plant. More
> J&J, Amazon fight shows supply-chain weakness in online sales. Story
> Actavis to close NC plant, trim 310 jobs. News
> Daiichi Sankyo says it was burned in Ranbaxy buyout. Article
> Alexion recalls more Soliris. Report
> More than 27M pharma units recalled in Q3. Item
Biotech Research News
> Report proposes revamping Alzheimer's R&D. More
> Japanese fund awards $5.7M in infectious disease vaccine work. Story
> Government shutdown effects on biomedical research outlined. Report
> MacroGenics to receive $9M from Boehringer Ingelheim in preclinical antibody pact. Item
> Compound mimicking gene deletion stops tissue scarring in mice. News
> New drug target identified for glioblastoma. Article