Alexza shares plunge on FDA extension; Verastem readies unusual biotech IPO;

@FierceBiotech: What's making Big pay for mobile tech? Drives to streamline trials ops and, of course, sell more drugs. Story | Follow @FierceBiotech

@JohnCFierce: Scientists strip the brake off of T cells in mouse study, amp up immune response. Article | Follow @JohnCFierce

@RyanMFierce: Educators jumping aboard the Big Data bandwagon with industry clamoring for help #bioinformatics--. Article | Follow @RyanMFierce

@MarkHFierce: B.U. has found some genetic triggers behind the onset of menopause. Info could help treat age-related diseases. Release | Follow @MarkHFierce

@FierceMedDev: An interesting read: Med tech consolidation brings a need for focus. Here are 2 ways to get it. Article | Follow @FierceMedDev

> Shares of Alexza Pharmaceuticals ($ALXA) slid 19% this morning after the biotech reported that the FDA had extended its review of the anti-psychotic Adasuve by three months. Report

> Spectrum Pharmaceuticals ($SPPI) reported some positive new data for its lymphoma drug Zevalin. Patients taking a Zevalin combo had a distinctly higher two-year survival rate compared to patients receiving chemo alone. Story

> The preclinical stage biotech Verastem plans to roll out an unusual $45 million IPO this week. In its SEC filings the biotech, which was founded by Christoph Westphal, has noted that the company's financial backers have committed to buying about a third of the offering. Story

> Exelixis ($EXEL) is claiming positive preliminary data from a Phase II study of cabozantinib in hepatocellular carcinoma. Release

Pharma News

@FiercePharma: Patent cliff + R&D disappointments + regulatory issues + economic woes = a tough 2012 for pharma, Fitch says. More | Follow @FiercePharma

> Tysabri label change could add $1B to sales. News

> Gov't probes laundry list of drugmakers. Story

> Roche workers protest contract hiring in Poland. News

> GSK chief wants Olympics lab to outlast games. Article

> Why drugmakers are so enamored of rare-disease meds. Item

Medical Devices News

> Stent advances expected to prop up European market. Story

> Covidien's Almeida to add title of chairman. Piece

> EU breast implant scandal may affect FDA's view on faster device approvals. Article

IT News

> Big Pharma testing waters with mobile tech. More

> Oracle injects genomics capability into analytics platform. News

> Medidata chief calls company 'the cloud' for clinical data. Story

> Consumers to pharma: Let's be Facebook friends (or not). Item

> Oracle, Parexel among leaders in CTMS market poised to hit $1.3B. More

> FDA brings new work flow software into its labs. Article

And Finally... Chinese officials have approved the world's first vaccine for hepatitis E. Story

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