Aastrom nears new financing for pivotal study; Jazz completes merger with Azur;

@FierceBiotech: Quintiles is pumping $4.6M into UK's Oxford Cancer Biomarkers as part of the CRO's push in personalized medicine. Article | Follow @FierceBiotech

@JohnCFierce: R&D taking a hit in Takeda layoffs, Bloomberg reports Konstanz, Germany facility affected. Anyone heard about other sites? Item | Follow @JohnCFierce

@FierceMedDev: GE ($GE) selects Bionime to launch innovative diabetes solutions. Release | Follow @FierceMedDev

@MarkHFierce: U.K. scientists are adapting a chemo drug to attach to other pills so it can be delivered by capsule or tablet. More | Follow @MarkHFierce

> Aastrom Biosciences CEO Tim Mayleben tells TheStreet the company is close to completing a financing that will fund a pivotal study on a new cell therapy for blocked leg arteries. Story

> Jazz Pharmaceuticals ($JAZZ) and Azur Pharma have completed their merger. The combined company now has 430 staffers. Release

GEN reports on the recent ups and downs of the U.K.'s biotech industry, including some new initiatives aimed at bolstering the sector. Report

> Courtagen Life Sciences has acquired Medicinal Genomics for an undisclosed sum. The genomics company has sequenced the entire genome of marijuana. Story

Pharma News

@FiercePharma: 2004 J&J memo asked reps to "flood clinics with Risperdal stuff" to boost off-label scripts for kids, TX says--Bloomberg. Story | Follow @FiercePharma

> Witness: J&J memo urged off-label Risperdal push. Item

> Novartis nabs Chinese OK for Lucentis, launches Galvus. Story

> Takeda targets 2,800 jobs in Europe, U.S. News

Drug Delivery News

> Kedem pursues version of Novartis' Gleevec that dissolves under tongue. Item

> 'Smart' nanotech may help treat Type 1 diabetes. More

> Genentech pursues sustained-delivery version of blockbuster eye drug Lucentis. Story

Medical Device News

> Boston Sci boasts of positive study results with Epic stent system. Article

> Ventana, Bayer to collaborate on companion Dx for cancer. News

> Blood test may help detect pancreatic cancer early. Item

> Covidien recalls device linked to 3 deaths during thoracic surgery. News

Biomarkers News

> Researchers inch closer to stomach cancer blood tests. Story

> Qiagen signs diagnostic biomarker deals. Article

> Biomarkers could improve treatment of neuroendocrine tumors. More

> Teams closing in on gene behind form of muscular dystrophy. Item

> Biomarkers making an earache less of a headache. Story

And Finally... Swedish investigators say the loss of sleep triggers a person's appetite by stimulating a specific region of the brain. "Bearing in mind that insufficient sleep is a growing problem in modern society, our results may explain why poor sleep habits can affect people's risk to gain weight in the long run." Release