Topic:

R&D

Latest Headlines

Latest Headlines

Meet some of the revolutionaries in biotech R&D

It's become a matter of commonly accepted faith in the biopharma biz that it takes more than $1 billion and 10 years to develop a new drug. Industry associations like to cite that factoid as a reason for the big prices we're seeing on new therapies, often while prodding the FDA for faster action. 

Forward Pharma pulls off a $221M IPO with eyes on unseating Biogen

Danish drug developer Forward Pharma came through with one of the year's biggest biotech IPOs, raising $221 million to support its plot to battle Biogen Idec in the blockbuster multiple sclerosis market.

Stealthy, DNA-based 'nano-cocoons' deliver cancer-killing payloads

Researchers at NC State University and the University of North Carolina have developed a DNA-based delivery vehicle capable of acting as a Trojan horse in cancer cells. Using DNA as a cage instead of synthetic materials makes the vehicle less toxic to healthy cells and allows for the attachment of precise targeting mechanisms.

Stem cell-derived beta cells deliver insulin in response to blood sugar levels

The self-regulation of insulin delivery is a long-sought goal in the field, spurring the development of closed-loop systems and an artificial pancreas for diabetics. But some researchers are aiming smaller, looking at a way to create stem cells en masse that can produce insulin in response to blood sugar levels.

Astellas dives into gene therapy with a Harvard expert in tow

Japan's Astellas Pharma is the latest big drugmaker allured by the promise of gene therapy, mounting an R&D effort that could lead to a new treatment for an inherited eye disease.

Flailing Wilex finds a lifeline as Roche steps in with an ADC deal

Germany's Wilex has long been on the way out of biotech, but a new collaboration with Roche provides the company with some cash up front and a shot at down-the-line royalties.

Alnylam trumpets early promise for its Sanofi-partnered RNAi drug

Alnylam's in-development RNAi treatment successfully staved off nerve damage related to a rare disease in an ongoing study, the biotech said, early but promising results as the company heads into Phase III with partner Sanofi in tow.

MGH investigator Tanzi claims breakthrough will 'revolutionize' Alzheimer's R&D

Massachusetts General Hospital investigator Rudy Tanzi has created a new "Alzheimer's-in-a-dish" approach to growing brain cells that he claims provides clear proof of the much-debated amyloid hypothesis as well as a solid target for the disease. And now he reportedly plans to race ahead with his new research process to find a potential megablockbuster drug that can stop the disease in its tracks.

Covance and Novartis team up with eyes on Big Data

Covance has joined forces with Novartis to develop new ways to help drug developers quickly integrate and analyze huge swaths of study data.

Harvard scientists develop super-repellent device coating

As med tech companies search for innovative ways to improve device implantation and patient outcomes, a new coating technology from Harvard University scientists could reduce blood clotting and bacterial infection associated with commonly used medical devices.