Topic:

Clinical Trials

Latest Headlines

Latest Headlines

Targacept shares crater after another program goes down in flames

After a steady drumbeat of setbacks over the past two years, the Winston-Salem, NC-based biotech says it will tamp down the last spade of dirt on TC-5619 after the therapy--which already failed a study for ADHD--flunked the primary as well as secondary endpoints in a Phase IIb study for schizophrenia.

CROS NT names a new CEO amid its global push

Come January, Italy's CROS NT will have a new CEO, as Andrew MacGarvey will take the reins from longtime chief Paolo Morelli.

Bayer teams up with Texas' MD Anderson for cancer clinical trials

Global pharma giant Bayer has inked a three-year deal with the University of Texas' MD Anderson Cancer Center to run clinical trials, matching its investigators with patient-serving oncologists in a deep-seated collaboration.

AbbVie's veliparib wows in a breast cancer study

AbbVie's PARP inhibitor veliparib improved outcomes for women with triple-negative breast cancer in a new investigator-sponsored study, charting a 52% complete response rate.

Aveo: Tivozanib doesn't do much for colorectal cancer, either

Aveo Oncology's long-troubled tivozanib is unlikely to meet its primary endpoint in a study on colorectal cancer, the company said, sending the biotech back to the drawing board after a high-profile failure in kidney cancer.

AstraZeneca gets some good news for its late-stage gout therapy

AstraZeneca's gout drug lesinurad hit its primary endpoint in a Phase III trial, the company said, a welcome turn for one of the drugmaker's top prospects amid a thin slate of late-stage therapies.

Lundbeck teams with Otsuka on Alzheimer's vaccine development

The vaccine, which is designed to work through early inhibition of amyloid beta depositions, is due to enter Phase I trials next year.

ImmunoCellular tanks after cancer vaccine flops on key endpoint in PhII

ImmunoCellular Therapeutics put out the word Wednesday afternoon that its dendritic cell-based vaccine for brain cancer flunked the key overall survival test in Phase II, news that swiftly wiped out more than half of the small biotech's market cap as shares instantly cratered.

Oxygen Bio taps Duke's in-house CRO to run Phase III for its cardio drug

Duke University leads the way among schools with on-campus CROs, and now Oxygen Biotherapeutics has entrusted the institution with handling late-stage studies of its promising heart drug.

Avanir hits the skids after its pain drug flunks a mid-stage study

Avanir Pharmaceuticals watched its shares tank more than 20% after its lead pain candidate failed to outdo a placebo in a Phase II study of patients with multiple sclerosis.