Topic:

Clinical Trials

Latest Headlines

Latest Headlines

Quintiles and Quest team up for lab testing with $575M JV

Months after LabCorp acquired its rival Covance, Quintiles has signed a sweeping agreement with lab testing giant Quest Diagnostics to launch a joint venture focused on clinical trials.

Ohr Pharma's eye drop fails a Phase II AMD trial

Ohr Pharmaceutical, at work on an eye drop to complement the blockbuster Lucentis, watched its top prospect fail to meet the main goal in a Phase II trial, dimming hopes for the drug's future.

Conatus heralds success for its NASH drug and plots Phase III

San Diego's Conatus Pharmaceuticals said its in-development liver disease drug came through in a Phase II trial, results the company believes create a path to late-stage development.

GlaxoSmithKline takes TB vaccine to Phase IIb

BCG (Bacille Calmette-Gu é rin) is the only WHO-approved tuberculosis vaccine and is given to infants, but has proven ineffective in adults. Enter GlaxoSmithKline, which, along with Aeras and Kenya Medical Research Institute, will roll their candidate in Phase IIb trials in Kenya.

Chinese Ebola vaccine based on current strain looks safe in PhI

Results from the Phase I trial of yet another experimental Ebola vaccine are in, but unlike other vaccines in the field, this one is based on the virus strain that caused the 2014 epidemic, and not an older one. The vaccine, developed by Beijing Institute of Biotechnology and Tianjin CanSino Biotechnology, is called a recombinant adenovirus type-5 vaccine.

MEI's second go at cancer R&D flunks a Phase II MDS trial

MEI Pharma's lead candidate failed to meet its primary goal in a Phase II study on myelodysplastic syndrome, a rare bone marrow disorder that often develops after cancer treatment, sending the biotech trawling for a positive spin on the data.

GSK to test Ebola jab with booster from Emergent BioSolutions

GlaxoSmithKline is testing its Ebola jab in Africa to see if it provokes an immune response strong enough to successfully beat an Ebola infection. But if it turns out to be too weak, never fear--the Big Pharma has a plan. It's teaming up with Maryland-based Emergent BioSolutions to test the latter's Ebola shot as a booster for its own vaccine.

Deep dive into Actelion's Uptravi data calms investors as FDA decision date nears

Actelion has presented detailed data on the drug it hopes will cement its position in the pulmonary arterial hypertension market, Uptravi. The shock-free data drove a small uptick in Actelion's stock, but fell short of being the blockbuster-guaranteeing release some were hoping to see.

Nektar looks for the positive in a failed PhIII breast cancer study

About two months ago, Nektar was talking up a big expansion, making way for the new staffers that would be needed to start commercializing the breast cancer drug NKTR-102. Today, the biotech may be rethinking that plan, as the drug failed in a pivotal late-stage study.

Combo-happy Diamyd launches new diabetes vaccine trial in children

Diabetes vaccine developer Diamyd Medical is running a Phase II test to see if its candidate, Diamyd, can prevent or delay the onset of Type 1 diabetes in children at very high risk of presenting with the disease.