Topic:

Clinical Trials

Latest Headlines

Latest Headlines

Synexus wins Pfizer's favor for South African trials

Patient-recruitment specialist Synexus has won a place in Pfizer's stable of preferred providers, giving the company advance information about future clinical trials and a leg up on other outsourcers.

UPDATED: Eli Lilly racks up another Alzheimer's failure after BACE drug sparks safety fears

In yet another indication of the yawning gap between what drug developers know about Alzheimer's and how it could be treated, Eli Lilly today decided to scrap its Phase II study for a BACE inhibitor after gathering abnormal liver tests from patients.

UPDATED: GlaxoSmithKline slams brakes on trial of MS drug linked to data scandal

GlaxoSmithKline has stopped development of an experimental drug for multiple sclerosis after a preclinical study turned out to contain "misrepresentations" in data from its R&D labs in China.

Lilly's oral rheumatoid arthritis blockbuster contender champions 1-year study

Efficacy results for an experimental rheumatoid arthritis drug in development by Eli Lilly and Incyte held up well as patients in a Phase IIb trial were tracked over the course of a full year.

Amgen notches positive PhIII results for top cancer drug

Once again, Amgen's R&D chief Sean Harper has Roger Perlmutter to thank for a positive late-stage outcome on one of the Big Biotech's top cancer prospects.

Latin American cancer vax races Big Pharma rivals

The lung cancer vaccine race has brought together an unusual mix of players. Merck KGaA was in a good position, but its vaccine disappointed in Phase III, while GlaxoSmithKline could report data on its candidate this year. Then there is the Cuba-Argentina joint venture.

GlaxoSmithKline's research chief in China fired for data fraud

The head of GlaxoSmithKline's R&D operation in China has been fired while another researcher has resigned following a company probe into allegations that data on interleukin-7 research published in Nature Medicine was "misrepresented" by company researchers.

FDA lifts clinical hold on anthrax vaccine

The FDA has lifted the clinical hold on PharmAthene's anthrax vaccine candidate, SparVax.

FDA clamps clinical hold on Pluristem PhII stem cell trial

One of the patients enrolled in a mid-stage study for an experimental stem cell therapy from Pluristem Therapeutics suffered a severe allergic reaction, sending him to the hospital and prompting FDA officials to clamp a clinical hold on the study.

Sanofi takes $285M charge after racking up back-to-back PhIII trial failures

Sanofi's iniparib failed a Phase III study for squamous non-small cell lung cancer, the final strike against a once-promising drug that has proved a bitter disappointment for the pharma giant.