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News

Shire to buy Jerini in $521M deal

With an eye toward snapping up a late-stage orphan drug for hereditary angiodema - a rare genetic disease -- Shire has agreed to pay $521 million to acquire Berlin-based Jerini AG. That's a whopping... Read more...

Mixed data for Renovo's scarring therapy

Renovo's Juvista produced a mixed set of data in two mid-stage trials. The drug produced positive data in reducing scarring but failed to demonstrate efficacy during a breast augmentation trial.... Read more...

Shire, Amicus forge $440M pact

Amicus Therapeutics has scored a $50 million upfront payment from Shire's human genetics sub for rights outside the U.S. to three experimental therapies for genetic disorders: Amigal (migalastat... Read more...

ALSO NOTED: Big CEO turnover at Big Pharma; New company takes on RNAi field; Shire hunts for buyouts; and much more...

> Turnover at the top of Big Pharma has been running at an unprecedented pace. And now, with fresh faces at the helm at nine of the world's top 12 pharma companies, there's a new generation... Read more...

3. Shire and Renovo

Who: Shire With: Renovo What: $875 million Summary: Shire forked over $75 million up front along with a $50 million equity payment to Renovo as part of an $875 million deal for the exclusive... Read more...

Shire to Massachusetts: Pass incentive bill now

The Massachusetts Legislature is taking its sweet time passing Governor Deval Patrick's proposed $1 billion incentive bill, and... Read more...

ALSO NOTED: Avandia gets Black Box Warning; Shire licensing deal complete; Pittsburgh companies gain financing; and much more..

> Hang the black crepe: the FDA has ordered new "black box" warning labels for Avandia and its Japanese cousin Actos. ... Read more...

Noven garners $25M payday on sales milestone

Noven will pocket the second of three potential $25 million milestones outlined in its deal with Shire. Shire says that the ADHD drug Daytrana continues to rack up enough market share to trigger the... Read more...

ALSO NOTED: CRO market hits $14B; Merck ends BioXell pact; and much more...

> Merck has ended its collaboration with BioXell on its sepsis drug TREM-1. BioXell says it will seek another company with which to partner on the drug. Report > Shire... Read more...

Progeria trial underscores challenge of rare diseases

The mother of a young boy with Progeria has paved the way to the world's first clinical trial into a potential treatment of the disease, which will require recruiting more than half of the 42 known patients in the world. The case underscores both the promise of new genetic research into potential treatments as well as the challenges researchers face in studying rare diseases. Progeria affects only one in every four million to eight million children, most of whom die from a stroke or heart …

... Read more...

Press Releases

Shire Announces Results from a Multidisciplinary Analysis of the Drug Release Profiles of LIALDA (mesalamine) and Asacol

Shire Announces Results from a Multidisciplinary Analysis of the Drug Release Profiles of LIALDA(R) (mesalamine) and Asacol(R) PHILADELPHIA, Oct. 6 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP; Read more >>

PRESS RELEASE: Amicus Therapeutics, Inc. and Shire Pharmaceuticals Group Enter Into $440 Million ex-US Licensing Agreement

Amicus Therapeutics and Shire Pharmaceuticals Group Enter Into $440 Million ex-US Licensing Agreement CRANBURY, N.J., Nov. 8 -- Amicus Therapeutics, Inc. announced today that it has entered into a Read more >>

PRESS RELEASE: Shire Pharmaceuticals Group's Fosrenol Does Not Meet Main Goal of Trial

Shire Pharmaceuticals Group's Fosrenol Does Not Meet Main Goal of Trial PHILADELPHIA and BASINGSTOKE, England, November 6 -- Shire plc today announced the results of a Phase II study indicating that Read more >>

PRESS RELEASE: Shire Voluntarily Withdraws a Limited Portion of Daytrana (Methylphenidate Transdermal System) Patches

Shire Voluntarily Withdraws a Limited Portion of Daytrana (Methylphenidate Transdermal System) Patches Patches that are easier to use are available for patients and their families PHILADELPHIA, Read more >>

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