Portola Pharmaceuticals' anti-anticoagulant came through in a pair of Phase III trials, rapidly reversing the effects of blood thinners Xarelto and Eliquis and setting the stage for a final FDA submission.
Portola Pharmaceuticals has laid out the last batch of Phase III data on its "breakthrough" anti-anticoagulant andexanet alfa, filling in the numbers that will be reviewed by regulators considering the biotech's upcoming pitch for marketing approval. And right alongside that announcement comes the latest numbers from Boehringer Ingelheim's breakthrough program for idarucizumab, which is already under review as an antidote to its blockbuster Pradaxa.
Portola Pharmaceuticals has snapped in the last piece to a Phase III program puzzle for its "breakthrough" anti-anticoagulant, painting a clear path to an accelerated regulatory submission later in the year.
Portola Pharmaceuticals' antidote to Big Pharma's latest crop of blockbuster blood thinners hit the mark in its first Phase III trial, clearing the way for an FDA submission next year.
Portola Pharmaceuticals' promising antidote for blood thinners has attracted a who's-who of Big Pharma partners, and now the biotech is advancing its reverser of Factor Xa inhibitors to Phase III with the help of Bayer and Johnson & Johnson.
South San Francisco-based Portola Pharmaceuticals has nabbed boasting rights to the FDA's new breakthrough drug designation for andexanet alfa (PRT4445), its Factor Xa inhibitor antidote designed to hit the brake on blood thinners when they turn dangerous.
Last year when we did the list of the top 10 biotech IPOs of 2012, we were lucky to have 10. Actually, there were 11, and that looked pretty good compared to the lean and hungry years of 2008 to...
The list of biotechs going public grows longer. With public investors warming to biotech IPOs, Portola Pharmaceuticals has proposed a public debut with a relatively sizable maximum aggregate offering amount of $115 million.
What would top Xarelto for Bayer and Johnson & Johnson? Xarelto with an easy antidote.
Portola Pharmaceuticals has signed on to see if its antidote to Factor Xa inhibitors--PRT4445--will help make the blood-thinner Xarelto safer.