C&L: Pigliucci resigns as CEO of Discovery Partners

Riccardo Pigliucci has resigned as CEO and chairman of Discovery Partners. Harry F. Hixson, Ph.D., currently the company's lead independent director, has assumed the role of chairman of the board and Michael C. Venuti, Ph.D., has been appointed the acting CEO.

Encysive Pharmaceuticals has appointed George W. Cole as COO. Cole previously served for more than 10 years in senior management roles with Altana Pharma US.

Daniel S. Lynch resigned as CEO and Director of ImClone Systems. Philip Frost, M.D., Ph.D., currently executive vice president and chief scientific officer, will serve as interim CEO while the board looks for a permanent replacement.

POZEN has named Everardus Orlemans, Ph.D., as vice president, clinical research. Most recently, Dr. Orlemans was executive director of the clinical development unit for Organon in the US.

J. Kris Piper has joined Xanthus Life Sciences as vice president of regulatory affairs and quality assurance. He had been vice president global preclinical and clinical regulatory affairs at Bracco.

Mpex Pharmaceuticals hired Mike Dudley, Pharm.D., as vice president of drug development. He had been vice president, preclinical and clinical sciences at Diversa.

PAREXEL International has appointed Glenn C. Van Deusen corporate vice president and general manager of medical marketing services. Van Deusen joined PAREXEL from Publicis Groupe.

Eurand has named Dr. Costantinos Efthymiopoulos, formerly a vice president with Serono, to the position of chief scientific officer.

Abgenix has named Jeffrey H. Knapp senior vice president of sales and marketing. For the majority of his executive career, Knapp held several positions of increasing responsibility at Eli Lilly.

FibroGen has named Russell H. Ellison as vice president of clinical development. Dr. Ellison was most recently vice president of medical affairs and chief medical officer at Sanofi-Synthelabo.

Immtech International has appointed Dina Grinshpun as vice president, general and IP Counsel. Ms. Grinshpun previously worked at Fish & Richardson P.C.

MonoSolRx has hired Madhu Hariharan, Ph.D, and Bruce Detwiler from Abbott Laboratories and Cardinal Health, respectively. Dr. Hariharan joins MonoSolRx as director, product development. Bruce Detwiler joins as packaging engineer.

Schering-Plough has named Andre van de Sande general manager of Schering-Plough Netherlands based in Utrecht.

AlgoRx Pharmaceuticals and Corgentech named Robert L. Zerbe, M.D., as the ninth board member for the combined company.

Novacea appointed Daniel M. Bradbury to the company's board of directors.

AVANIR Pharmaceuticals has elected Scott M. Whitcup, M.D., to the company's board of directors to fill a vacancy resulting from the resignation of Kenneth E. Olson.

Cylex Incorporated has named Thomas Bologna to its board of directors.

Protalex has appointed Peter G. Tombros to the company's board of directors.