ADX10061--Addex Pharmaceuticals' smoking cessation drug--did not meet the primary efficacy endpoint in a Phase IIa. The primary endpoint was to assess whether the drug increased the number of patients with four weeks continuous smoking abstinence starting from the beginning of week four of treatment. There was no difference between patients treated with ADX10061 and placebo. Addex has abandoned development of the drug.
Earlier this year Addex launched a successful IPO; the company's stock took a hit on the trial data news. Addex is also developing therapies for gastroesophageal reflux disease and migraine.
- see this release [1]Â from Addex
Related Articles:
Addex pockets $111M in successful IPO. Report [2]
Scientists identify path to addiction drug therapy. Report [3]
Links:
[1] http://www.fiercebiotech.com/press-releases/press-release-addex-pharmaceuticals-announces-adx10061-phase-iia-smoking-cessation-da
[2] http://www.fiercebiotech.com/story/addex-pockets-111m-in-successful-ipo/2007-05-22
[3] http://www.fiercebioresearcher.com/story/scientists-identify-path-to-addiction-drug-therapy/2007-04-03