ImClone has been buoyed by the news that Erbitux plus chemotherapy was better than chemotherapy alone in progression-free survival of colon cancer. Patients in the late-stage study given Erbitux and irinotecan demonstrated a 54 percent improvement in patient survival without new tumor growth. That was a secondary endpoint. The primary endpoint of overall mortality was not achieved. A second trial showed that Erbitux alone improved survival times and slowed tumor growth. Professor Derek Joner, co-chair of the study and assistant professor at the University of Ottawa, said that this was the first time that a single therapeutic proved effective in improving survival times.
- check out this release [1] on the data
- for more, read the report [2] from Crain's New York Business
Related Articles:
Erbitux data could gin extra $350M in sales. Report [3]
Erbitux approved for head and neck cancers. Report [4]
Analysts raise doubts on Erbitux ruling. Report [5]
ImClone touts survival rate in Erbitux cancer trial. Report [6]
Links:
[1] http://www.fiercebiotech.com/node/6520
[2] http://www.newyorkbusiness.com/apps/pbcs.dll/article?AID=/20070416/FREE/70416010/1045
[3] http://www.fiercebiotech.com/story/erbitux-data-could-gin-extra-350m-in-sales/2007-04-05
[4] http://www.fiercebiotech.com/story/erbitux-approved-for-head-and-neck-cancers/2006-03-02
[5] http://www.fiercebiotech.com/story/analysts-raise-doubts-on-erbitux-ruling/2006-09-20
[6] http://www.fiercebiotech.com/story/imclone-touts-increased-survival-rate-in-erbitux-cancer-trial/2005-11-16