> The FDA has approved Cleviprex--an intravenous blood pressure drug--from The Medicines Company. Story [1]
> Expression Genetics has completed its $12-million Series B financing. The final, $7 million portion of the financing was secured in July. The money will be used to fund the clinical development of its lead product--the cancer therapeutic EGEN-001--and to further advance its development of delivery technologies for siRNA and shRNA. Release [2]
> Affymetrix says it will close its manufacturing facility in West Sacramento and relocate the operations to Singapore. Report [3]
> The new execs taking control at MiddleBrook Pharmaceuticals may move the company from Maryland to Texas. Report [4]
> Los Altos, CA-based Interkrin Therapeutics has secured $18.25 million of a 26.14 million Series C. Story [5]
> Two drugmakers' hometown newspapers offer a rundown on the litigation they face over sales tactics: For AstraZeneca, it's allegations of improperly marketing Seroquel, and for Abbott, more claims over its pricing of the AIDS med Norvir. Report [6]
> Analysts just can't get their minds off which drugmakers might make a deal next. The most recent suspects are Bayer and Onyx, which are partnered on the liver and kidney cancer med Nexavar [7]. Report [8]
> hould HIV drugs be used to prevent infection with the deadly virus? Given the fact that vaccine developers have to start all over on their anti-HIV shot [9], and microbicides haven't shown much promise either, prophylactic use of antiretroviral drugs seems like a logical choice. Report [10]
> GaxoSmithKline is doing some fancy number-crunching in an attempt to get the U.K. to cover its cancer med Tyverb [11] (sold as Tykerb in the U.S.). According to the Financial Times, GSK is working on a pioneering deal that would cap the cost of Tyverb--no matter how many patients sign on to use it. GSK report [12]
And Finally... Overall, job prospects for new college grads are bleak, but hiring in biotechnology remains strong. Article [13]
Links:
[1] http://www.thestreet.com/s/fda-oks-medicines-cos-cleviprex/newsanalysis/drugs/10431709.html?puc=googlen&cm_ven=GOOGLEN&cm_cat=FREE&cm_ite=NA
[2] http://www.fiercebiotech.com/press-releases/expression-genetics-inc-specializing-dna-rnai-delivery-and-therapeutics-completes-1-0
[3] http://www.sacbee.com/140/story/1127609.html
[4] http://washington.bizjournals.com/washington/stories/2008/08/04/story19.html?b=1217822400^1678030
[5] http://www.pehub.com/article/articledetail.php?articlepostid=13787
[6] http://www.fiercepharma.com/story/abbott-faces-more-aids-suits/2008-08-04
[7] http://www.fiercepharma.com/story/bayer-stops-nexavar-lung-cancer-trial/2008-02-19
[8] http://www.fiercepharma.com/story/bid-happy-analysts-play-matchup/2008-08-04
[9] http://www.fiercebioresearcher.com/vaccines/story/aids-vaccine-researchers-years-away-from-success/2008-04-24
[10] http://www.fiercepharma.com/story/hiv-drugs-may-find-preventive-use/2008-08-04
[11] http://www.fiercebiotech.com/special-reports/tykerb-2007-fda-approvals
[12] http://www.fiercepharma.com/story/gsk-offers-u-k-fixed-price-tyverb/2008-08-04
[13] http://www.washingtonpost.com/wp-dyn/content/article/2008/08/02/AR2008080200127.html