FierceBiotech and FiercePharma Jobs
Director of Platform Technology - RXi Pharmaceuticals Corporation
Dec 10
Location: Worcester, MACategories: Administrative
Website: http://www.rxipharma.com
Position Description
RXi Pharmaceuticals (NASDAQ: RXII) is a biopharmaceutical company pursuing the development and commercialization of proprietary therapeutics based on RNA interference (RNAi) for the treatment of serious human diseases. RXi was founded in January of 2007 by leaders in the RNAi field including Dr. Craig Mello, recipient of the 2006 Nobel Prize for Medicine for his co-discovery of RNAi.
As the Director of Platform Technology, you will be an integral part of an interdisciplinary project team working toward the common goal of developing RNAi compounds for therapeutic use. Your main responsibility will encompass the critical evaluation and optimization of RNAi compounds and delivery technologies for RNAi therapy in a variety of disease areas. You will identify, initiate and manage new technology collaborations to assess and prioritize delivery modalities, direct the development of in-house formulation work, and oversee in vivo evaluation in collaboration with our Pharmacology group. In this central role, you will contribute leadership and support to internal programs as well as external partnerships, and facilitate the advancement of research stage compounds into development.
Qualifications:
• Ideal candidates have a Ph.D. in Molecular Biology, Biochemistry, Chemistry or related discipline and 10 years of post-degree research experience with >5 in a biotech/pharmaceutical industrial setting.
Additional Job Requirements Include:
• Comprehensive understanding of current oligonucleotide delivery technology and knowledge of the critical challenges for the intracellular delivery of synthetic oligonucleotides in target tissues in vivo
• Expertise in the oligonucleotide therapeutic space relating specifically to the design and use of modified synthetic oligonucleotides
• Drug formulation experience and proven track record in experimentally evaluating gene or oligonucleotide delivery systems in animal models
• Proven track record in developing novel and practical technologies in the area of oligonucleotide therapeutics and/or molecular medicine in general
• Strong managerial experience and demonstrated success overseeing multiple projects
• Creative and critical thinking; effective oral and written communication
• Practical understanding of technology licensing and drug development
We offer a competitive salary and a generous benefits package including medical, dental, vision and life insurance, flexible spending accounts, stock options, holidays and paid time off.
